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Rivaroxaban is a highly selective, oral drug that directly inhibits factor Xa. By inhibiting factor For the prevention of venous thrombosis in adult patients undergoing elective hip or knee replacement surgery.

So, how to take rivaroxaban?

(1) Dosage for hip and knee replacement: 10 mg once a day for 35 days and 12 days for knee replacement.

(2) How to take DVT and PE: On days 1 to 21, take 15 mg and 30 mg twice a day, and on days 22 and after, take 20 mg and 20 mg once a day, respectively.

(3) Dosage for non-valvular atrial fibrillation: 20 mg once a day. For patients with low body weight and advanced age (>75 years old), 15 mg can be used as appropriate, once a day.

(4) The 10 mg tablet can be taken on an empty stomach or with food; the 15 mg or 20 mg tablet should be taken with food.

(5) If the whole tablet cannot be swallowed, crush the tablet, mix it with applesauce and take it orally immediately.

(6) If a missed dose occurs, the dose should be taken immediately and the dose should not be doubled in one day to make up for the missed dose.

Can special groups of people take rivaroxaban?

(1) Pregnant and lactating women: Disabled.

(2) Children: Not recommended for use by children under 18 years old.

(3) Elderly: Patients over 75 years old should reduce the dosage appropriately and please use it under the guidance of a physician or pharmacist.

Medication monitoring of rivaroxaban:

Rivaroxaban's anticoagulant effect is predictable, has a wide therapeutic window, no accumulation after multiple doses, and few interactions with drugs and food, so routine coagulation monitoring is not required.

Under special circumstances, such as suspected rivaroxaban overdose, severe bleeding events, emergency surgery, thromboembolic events, or suspected poor compliance, prothrombin time (PT) or anti-factor Xa activity needs to be determined.