Rivaroxaban适应症有什么呢？

It is a highly selective, oral drug that directly inhibits factor Xa. By inhibiting factor The recommended dose of Rivaroxaban is Rivaroxaban 10 mg orally once daily. If the wound has stopped bleeding, the first medication should be administered between 6-10 hours after surgery. The length of treatment is determined by each patient's risk of VTE, i.e. by the type of orthopedic surgery the patient has undergone.

Rivaroxaban, a new anticoagulant drug from Bayer Healthcare of Germany, can effectively reduce the formation of venous thrombosis in patients after major orthopedic surgery, and its efficacy is better than the current standard therapy of enoxaparin. Statistics show that without preventive treatment, up to 60% of patients may develop venous thrombosis, leading to various malignant consequences including death. According to Bayer, compared with traditional drugs that require injection or continuous monitoring, Rivaroxaban can be taken directly and does not require monitoring, making clinical treatment more convenient.

Rivaroxaban indications:

1. For use in adult patients undergoing elective hip or knee replacement surgery to prevent venous thrombosis (VTE).

2. Used to treat venous thrombosis (DVT) in adults and reduce the risk of DVT recurrence and pulmonary embolism (PE) after acute DVT.

3. For use in adult patients with nonvalvular atrial fibrillation who have one or more risk factors (e.g., congestive heart failure, hypertension, age ≥75 years, diabetes, history of stroke or transient ischemic attack) to reduce the risk of stroke and systemic embolism.

Rivaroxaban received marketing approval in Canada and the European Union on September 15 and October 1, 2008, respectively. Rivaroxaban was approved for marketing by the State Food and Drug Administration in March 2009. Approved by the FDA on July 1, 2011, the drug is used to prevent deep vein thrombosis in patients undergoing knee or hip replacement surgery.

The recommended dose is Rivaroxaban 10 mg orally once daily. If the wound has stopped bleeding, the first medication should be administered between 6-10 hours after surgery. The length of treatment is determined by each patient's risk of VTE, i.e. by the type of orthopedic surgery the patient has undergone. For patients undergoing major hip surgery, a recommended course of treatment is 5 weeks. For patients undergoing major knee surgery, a recommended course of treatment is 2 weeks. If a dose is missed, the patient should take Rivaroxaban immediately and continue taking it once a day the next day. Patients can take Rivaroxaban with a meal or alone.

The above is the content of the indications, I hope it can help you.