Xarelto用法用量

Rivaroxaban (Xarelto) is used to prevent the formation of deep vein thrombosis (DVT) and pulmonary embolism (PE) in patients following hip and knee replacement surgery. It can also be used to prevent stroke and non-central nervous system embolism in patients with non-valvular atrial fibrillation, and reduce the risk of recurrence of coronary syndrome. 

Rivaroxaban (Xarelto, Xarelto) usage and dosage: 1. To prevent venous thrombosis in adult patients undergoing elective hip or knee replacement surgery: the recommended dose is oral rivaroxaban (Xarelto, Xarelto) 10 mg, once a day. If the wound has stopped bleeding, the first dose of medication should be between 6 and 10 hours after surgery. For patients undergoing major hip surgery, the recommended course of treatment is 35 days. For patients undergoing major knee surgery, the recommended course of treatment is 12 days. If a missed dose occurs, patients should take rivaroxaban (Xarelto) immediately and continue taking the drug once daily the next day. 2. Treat DVT and reduce the risk of acute DVT recurrence and PE: The recommended dose for the initial treatment of acute DVT is 15 mg twice a day for the first three weeks, and then the dose for maintenance treatment and to reduce the risk of DVT recurrence and PE is 20 mg once a day. In the later stage, the current view is that it can also be taken in small doses, namely 10mg, once a day. 3. After carefully evaluating the benefits of treatment and the risk of bleeding, the duration of treatment should be determined based on individual circumstances. Short-term treatment (3 months) should be based on transient risk factors (eg, recent surgery, trauma, immobilization), and long-term treatment should be based on permanent risk factors or idiopathic DVT. If a missed dose occurs during 15 mg twice daily treatment (Days 1-21), patients should take rivaroxaban (Xarelto, Xarelto) immediately to ensure that 30 mg of rivaroxaban (Xarelto, Xarelto) is taken daily. In this case, it may be necessary to take two 15 mg tablets at once. Thereafter, regular 15 mg twice daily dosing should be continued as recommended. If a missed dose occurs during 20 mg once-daily treatment (day 22 and beyond), the patient should begin rivaroxaban (Xarelto) immediately and should continue receiving rivaroxaban (Xarelto) at the recommended dose thereafter. The dose should not be doubled in one day to make up for a missed dose.