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Xarelto is a small molecule oral anticoagulant jointly developed by Bayer and Johnson & Johnson, with the trade name Xarelto. For the prevention of venous thrombosis (VTE) in adult patients undergoing elective hip or knee replacement surgery.
The four RECORD1-4 studies of Rivaroxaban to prevent VTE after total hip and knee replacement were a series of randomized, double-blind, multicenter clinical trials. The RECORD1-2 study evaluated the safety and effectiveness of rivaroxaban in preventing VTE in patients undergoing elective total hip arthroplasty. The results showed that compared with enoxaparin, rivaroxaban could significantly reduce the incidence of total VTE, major VTE and symptomatic VTE, while the incidence of major bleeding events and other bleeding events was similar in the two groups. The RECORD3~4 study compared the safety and effectiveness of the above two drugs in preventing venous thromboembolism in patients after elective total knee replacement. The incidence of the primary endpoint event in the enoxaparin group was 18.9%, while that of rivaroxaban was only 9.6%. The difference between the two was statistically significant (P<0.001). The results showed that the efficacy of Rivaroxaban group was not inferior to traditional treatment and the risk of bleeding was reduced.
Rivaroxaban administration: Orally. Rivaroxaban 10mg can be taken with food or alone. Can blood clots be dissolved by taking Xarelto Rivaroxaban Tablets?
It is the drug of choice for the treatment of venous thrombosis, but it is not thrombolysis. The purpose of anticoagulation is to prevent the formation of new thrombosis. This is the most important and primary treatment! Whether blood clots can be dissolved after taking Xarelto Rivaroxaban tablets depends on the patient's treatment effect. It is recommended that patients take the medication for a reexamination after 3 months to check the test results.
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