【简单超有用】2021年拜瑞妥（利伐沙班）药品使用说明

Xarelto (rivaroxaban) is a new oral anticoagulant that has many obvious advantages over other traditional drugs. Xarelto (rivaroxaban) can highly selectively and directly inhibit bound or free factor Xa, thereby interrupting the endogenous and extrinsic coagulation pathways, inhibiting thrombin production, and ultimately inhibiting thrombosis. As a new type of anticoagulant drug, Xarelto (rivaroxaban) is rapidly absorbed after oral administration, with an average half-life of 7 to 13 hours. It has the advantages of high bioavailability, stable anticoagulant effect, high selectivity, and obvious therapeutic effect. Patients can benefit greatly from taking this drug consistently. In a domestic study, 60 cases of deep vein thrombosis prevention after hip replacement were given Xarelto (rivaroxaban) and low-molecular-weight heparin respectively. The results showed that the incidence of DVT in the group was significantly lower, and the incidence of bleeding events was significantly lower than that of the low-molecular-weight heparin group. The control of platelet and coagulation levels was equivalent to that of low-molecular-weight heparin. Let’s take a look at the instructions for using Xarelto (rivaroxaban).

2021 Xarelto (rivaroxaban) Instructions for Use: Xarelto (rivaroxaban) to prevent venous thrombosis in adult patients undergoing elective hip or knee replacement surgery

The recommended dose is 10 mg of Xarelto taken orally once daily. If the wound has stopped bleeding, the first dose of medication should be between 6 and 10 hours after surgery. 

For patients undergoing major hip surgery, the recommended course of treatment is 35 days. For patients undergoing major knee surgery, the recommended course of treatment is 12 days. If a missed dose occurs, patients should take Xarelto immediately and continue taking the dose once daily the next day.

For use in adult patients with non-valvular atrial fibrillation to reduce the risk of stroke and systemic embolism

The recommended dose of Xarelto is 20 mg once a day, which is also the maximum recommended dose. For patients with low body weight and advanced age (>75 years old), doctors can use 15 mg once a day as appropriate based on the patient's condition. 

Xarelto treats DVT (venous thrombosis) and reduces the risk of acute DVT recurrence and PE

The recommended dose for initial treatment of acute DVT is 15 mg twice daily for the first three weeks, followed by 20 mg once daily for maintenance treatment and to reduce the risk of recurrent DVT and PE. 

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

  Recommended related articles: