康护乐小编告诉您如何正确使用抗凝药物利伐沙班

In recent years, domestic and foreign guidelines have recommended new oral anticoagulants as the first choice for secondary prevention of cerebral infarction in patients with non-valvular atrial fibrillation and cerebral infarction. It is a factor Xa inhibitor that can selectively block the active site of factor Xa to exert anticoagulant activity and prevent thrombosis. In recent years, studies have shown that inflammatory factors may be one of the pathogenesis mechanisms of atrial fibrillation, participating in the occurrence and development of atrial fibrillation through immune mechanisms, regulating cell growth and differentiation mechanisms, and other pathways.

Rivaroxaban is an oral factor Xa inhibitor that does not require cofactors. It is specific and competitive, acting directly on the active site of factor Xa, inhibiting both free and bound factor Xa, and inhibiting the generation of thrombin. The ROCKETAF study shows that when rivaroxaban is used to prevent stroke and systemic embolism in patients with non-valvular atrial fibrillation, it has better efficacy and good safety during treatment, and can significantly reduce the incidence of intracranial hemorrhage and fatal bleeding.

Regarding rivaroxaban, many people do not know how to use this drug correctly. Today, let the editor of Medical Companion Travel tell you how to use rivaroxaban correctly.

For adult patients with non-valvular atrial fibrillation to reduce the risk of stroke and systemic embolism: 20 mg once a day, which is also the maximum recommended dose. For patients with low body weight and advanced age (>75 years old), doctors can use 15 mg once a day as appropriate based on the patient's condition. Common side effects of this drug are: bleeding, abdominal pain, heavy bleeding, dizziness, fatigue, depression, back pain, syncope, skin blisters, muscle spasms, bronchiectasis, elevated serum aminotransferases, insomnia, anxiety, limb pain, pulmonary bleeding, wound secretions, itching, etc.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.