拜瑞妥副作用及处理

It can selectively and directly inhibit bound or free factor Xarelto is produced by Bayer Healthcare Co., Ltd. Clinically, rivaroxaban has gradually replaced warfarin as the anticoagulant drug of choice for venous thrombosis, atrial fibrillation, pulmonary embolism and other diseases. Today we will learn more about the side effects and treatment of Xarelto.

Xarelto side effects:

1. Bleeding risk; in the ROCKET AF trial, the most common adverse reaction related to permanent discontinuation was bleeding events, with an incidence rate of 4.3% in the Xarelto group and 3.1% in the warfarin group. The incidence of discontinuation due to non-hemorrhagic adverse events was similar in both treatment groups.

2. Spinal/epidural hematoma.

3. In patients with valvular atrial fibrillation, the risk of stroke increases after early discontinuation of medication;

4. Blood and lymphatic system diseases: agranulocytosis, thrombocytopenia;

5. Intestinal diseases: retroperitoneal bleeding;

6. Hepatobiliary diseases: jaundice, cholestasis, hepatitis (including liver cell damage);

7. Immune system diseases: hypersensitivity, allergic reaction, anaphylactic shock, angioedema;

8. Nervous system diseases: cerebral hemorrhage, subdural hematoma, epidural hematoma, hemiparesis;

9. Skin and subcutaneous tissue: Stevens-Johnson syndrome.

Rivaroxaban is contraindicated in patients with liver disease associated with coagulation abnormalities and clinically relevant risk of bleeding. Side effects are due to low drug selectivity and pharmacological effects involving multiple tissues and organs. When a certain effect is used as a therapeutic purpose, other effects become side effects. Side effects are predictable and generally unavoidable. Side effects are inherent effects of the drug itself and vary depending on the purpose of the treatment. Most are mild and disappear after stopping the drug. If you have mild side effects of Xarelto, you can decide whether to continue taking the drug based on your own situation. If you have serious side effects, you should inform your doctor or pharmacist as soon as possible.

  Xarelto is a highly selective, oral drug that directly inhibits factor xa. By inhibiting factor xa, the endogenous and exogenous pathways of the coagulation cascade can be interrupted, and the generation of thrombin and thrombosis can be inhibited. Xarelto does not inhibit thrombin and has no proven effect on platelets. 

The above is the content of side effects treatment, I hope it can help you!

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