Rivaroxaban副作用

Rivaroxaban is a new oral anticoagulant that prevents venous thrombosis. So, what are the side effects of using Rivaroxaban?

The most common side effect of Rivaroxaban is bleeding. All anticoagulant drugs have a risk of bleeding, but the probability of clinical major bleeding is relatively low.

Secondly, some patients may also experience skin reactions, and some patients may use Rivaroxaban, which may affect liver and kidney function to a certain extent, leading to an increase in creatinine and transaminases.

In addition, relatively rare side effects such as vascular abnormalities, abnormal platelet counts, and changes in coagulation function may occur.

Rivaroxaban contraindicated groups:

1. Patients who are allergic to Rivaroxaban or any excipients in the tablets.

2. Patients with clinically obvious active bleeding.

3. Lesions or conditions with a significant risk of major bleeding, such as current or recent gastrointestinal ulcers, malignant tumors with a high risk of bleeding, recent brain or spinal injury, recent brain, spine or eye surgery, recent intracranial hemorrhage, known or suspected esophageal varices, arteriovenous malformations, vascular aneurysms or major intravertebral intracranial vascular malformations.

4. Except for conversion to or from Rivaroxaban from other treatments, or administration of unfractionated heparin (UFH) doses required to maintain central venous or arterial catheters, concomitant treatment with any other anticoagulants is prohibited, such as UFH, low molecular weight heparins (enoxaparin, dalteparin, etc.), heparin derivatives (fondaparinux, etc.), oral anticoagulants (warfarin, apixaban, dabigatran, etc.).

5. Patients with liver disease associated with coagulation abnormalities and clinically relevant bleeding risks, including patients with cirrhosis reaching Child Pugh classes B and C.

6. Rivaroxaban is contraindicated in pregnant and lactating women.