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氢化可的松片(hydrocortisone)需要终身服用吗?

Author: Medicalhalo
Release time: 2025-10-19 11:44:20

(Alias: hydrocortisone) is used as a replacement therapy for the treatment of adrenal insufficiency and congenital adrenal hyperplasia. Do hydrocortisone tablets (hydrocortisone) need to be taken for life?

Hydrocortisone is a hormone. Generally speaking, it cannot be used for a long time. It should be used according to the condition. When used, it should be regularly observed by a doctor and the dosage should be adjusted at any time.

Long-term use of hydrocortisone can lead to Cushing's syndrome: moon face, hyperlipidemia, central obesity, purple lines, acne, diabetes tendencies, high blood pressure, osteoporosis, etc.

It is recommended to exercise moderately and eat more fruits and vegetables while taking hormones to increase the body's immunity.

Precautions for hydrocortisone:

1. Inducing infection: Patients with hypoadrenocortical hormone function are prone to infection. Under the influence of hormones, infections that have been controlled can become active. The most common case is the recurrence of tuberculosis infection. The application of hormones in certain infections can reduce tissue damage, reduce exudation, and alleviate the symptoms of infection and poisoning. However, it must be treated with effective antibiotics at the same time, and changes in the condition must be closely observed. After short-term use, the dosage should be quickly reduced and the medication should be discontinued.

2. Interference with diagnosis:

(1) Hydrocortisone can increase blood sugar, blood cholesterol, blood fatty acid, and blood sodium levels, and decrease blood calcium and blood potassium.

(2) The effects on peripheral blood include a decrease in the number of lymphocytes, eukaryotic cells, eosinophils and basophils, an increase in multinucleated leukocytes and platelets, and the latter may also decrease.

(3) Long-term use of large doses can cause false negative results in skin tests, such as tuberculin test, histoplasmin test and allergic reaction skin test.

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