肾上腺皮质增生症治疗新药-氢化可的松片

It is mainly used for the replacement therapy of adrenal insufficiency and the treatment of congenital adrenal hyperplasia. It can also be used for rheumatoid arthritis, rheumatic fever, gout, bronchial asthma, allergic diseases, and can be used for severe infection and anti-shock treatment.

Hydrocortisone tablets are glucocorticoid drugs. It has various pharmacological effects such as anti-inflammatory, anti-toxic, anti-shock and immunosuppressive effects. When there is a high clinical suspicion of acute adrenocortical crisis, treatment should be started immediately after blood specimens are taken and sent for ACTH and cortisol testing. Treatment includes administration of high-dose intravenous glucocorticoids; correction of hypovolemia and electrolyte imbalances; systemic supportive therapy and removal of triggers. Hydrocortisone phosphate or hydrocortisone succinate tablets (hydrocortisone) 100 mg can be injected intravenously first, and then 50 to 100 mg every 6 hours, with a total dose of 200 to 400 mg in the first 24 hours. When renal function is normal, hyponatremia and hyperkalemia are expected to correct after 24 hours. Most patients' conditions are under control within 24 hours.

Hydrocortisone tablets have been approved for marketing in China. As we all know, the high price is often one of the main factors that hinders the wider clinical application of hydrocortisone. It is currently known that the hydrocortisone tablets sold in Hong Kong, China, are currently the most cost-effective, about 1,000$.

This price is relatively cheap in comparison. Patients can not only benefit from it through continued treatment, but also reduce part of their out-of-pocket expenses. Moreover, based on the recommended drug dosage of 20-30mg per day, patients usually need to purchase 1-2 boxes of the drug a month. In this case, patients will need to spend 1,000-2,000$ a month on medication. This price is still within the acceptable range for many domestic patients.