磷酸二甲酯片(Astomin)的用法用量

The active ingredient of Astomin is dimethyl phosphate, which exerts a powerful antitussive effect by directly acting on the cough center.

Usage and Dosage of Dimethyl Phosphate Tablets (Astomin)

1. Standard dosage regimen

(1) Target population: This product is suitable for adults aged 15 years and above.

(2). Single dose: Take 1 to 2 tablets orally each time (equivalent to 10 mg to 20 mg of dimethyl phosphate).

(3). Medication frequency: 3 times a day.

(4) Basic recommendations: It is recommended to take it after meals with warm water to help reduce potential irritation to the gastrointestinal tract.

2. Principles of dose adjustment

(1) Based on symptoms: When cough symptoms are severe, a dose of 2 tablets per time may be considered; after symptoms are relieved, the dose can be reduced to 1 tablet per time for maintenance treatment.

(2) Based on age and physical condition: Especially for elderly patients (see Part 3 for details), since physiological functions may decline, the initial dose should be 1 tablet each time and the response should be closely observed.

3. Key medication warnings

It is packaged in an aluminum foil plate (PTP sheet). The tablets must be taken out of the aluminum foil plate before taking. It is strictly forbidden to swallow the whole tablet directly to avoid the sharp angle of the aluminum foil from stabbing the esophagus and causing serious complications such as perforation.

The pictures are from public channels (such as the official website of the FDA, the official website of the original drug manufacturer, etc.) and are for reference only.

Adverse reactions of dimethyl phosphate tablets (Astomin)

1. Common adverse reactions (incidence rate 1%-5%)

(1) Psychological nervous system: dizziness, drowsiness, headache or heavy head. This is the most common category of side effects. During medication, avoid driving, operating precision machinery, or working at heights.

(2) Digestive system: dry mouth, loss of appetite, nausea, vomiting, diarrhea. Most symptoms are mild and can be relieved by taking medication after meals.

2. Rare adverse reactions

(1) Psychological nervous system: fatigue and fatigue.

(2) Cardiovascular system: tachycardia, palpitations, facial flushing.

(3), allergic reaction: rash. Although the frequency is unknown, the drug should be discontinued immediately if it occurs.

3. Principles for handling adverse reactions

(1) Mild reactions: such as mild dry mouth and dizziness, symptomatic treatment can be taken (such as drinking more water, resting), and usually the body can gradually adapt.

(2) Reactions that require discontinuation of the medication and medical treatment: If rash, itching, severe palpitations, continued aggravation of dizziness or any other intolerable discomfort occurs, you should stop taking the medication immediately and consult a doctor or pharmacist in time.

Medication Guidelines for Special Populations of Dimethyl Phosphate Tablets (Astomin)

1. Elderly patients (elderly people)

The medication should be used with caution, and the initial dose should be reduced. The decline of physiological functions (especially liver and kidney functions) in the elderly may lead to slower drug metabolism and excretion, which may easily lead to drug accumulation in the body.

2. Pregnant women and women who may be pregnant

Use medication with caution. Only when the doctor clearly determines that the benefits of treatment to the mother far outweigh the potential risks to the fetus can they be considered for use. You must inform your doctor about your pregnancy before taking this medicine.

3. Breastfeeding women

The mother's treatment needs and the benefits of breastfeeding should be comprehensively considered, and the doctor and patient should jointly decide whether to continue breastfeeding or suspend medication.