默沙东新冠“特效药”莫努匹韦（Molnupiravir）引发关注！疗效如何？

New coronavirus pneumonia, referred to as new coronavirus pneumonia, refers to the pneumonia caused by the 2019 new coronavirus infection. The main symptoms of this disease are fever, dry cough, fatigue, etc. There are currently many cases around the world. It is an oral preparation that can treat the new coronavirus and reduce the risk of death. Today, let’s take a detailed look at the efficacy of Merck’s new coronavirus “special drug” Molnupiravir?

Merck is a global pharmaceutical giant, and Monupivir is produced and developed by Merck. Under the global pandemic of COVID-19, safe and effective vaccines are the line of defense against the epidemic, and antiviral drugs are also important tools. The emergence of Monupivir brings hope to patients with COVID-19. Molnupiravir can replace ribonucleosides during viral RNA replication, causing genetic mutations and thereby inhibiting the replication of various RNA viruses. The drug is a nucleoside analogue developed by Emory University in the United States. The drug has been studied several times in clinical trials.

So, how effective is Molnupiravir? In the Phase III MOVe-OUT study, 775 COVID-19 patients participated in the trial and received treatment with monopivir and placebo. The results showed that 28 of the 385 participants who received monopivir were hospitalized within 29 days after treatment, a rate of 7.3%. There were no death reports among patients who received monopivir; 53 of the 377 participants who received a placebo were hospitalized, a rate of 14.1%. The risk difference between the two was approximately 50%. There were eight deaths in the placebo group. This means that Molnupiravir reduced the risk of hospitalization or death in all major subgroups; efficacy was not affected by the timing of symptom onset or underlying risk factors. It can be seen that the therapeutic effect of this drug is significant.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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