默沙东新冠特效药用法？

At present, the main pathogenic strain of the novel coronavirus pneumonia (COVID-19) is the Omicron mutant strain of the 2019 novel coronavirus (SARS-CoV-2). Small molecule antiviral drugs developed by targeting key proteins in the viral cycle have become the current mainstream. Remdesivir, Molnupiravir, Nirmatrelvir/Ritonavir2, and S-217622 (Ensitrelvir) are the four most promising antiviral drugs that have been approved for marketing or are about to be launched. So, what is the use of Merck's specific COVID-19 drug?

How to use Merck’s new coronavirus specific medicine

Merck's COVID-19 specific drug is very simple. Usually, patients over 18 years old should take Mupiravir orally, 800mg each time, twice a day, for 5 days.

Notes for special populations

1. Persons with childbearing potential: Instruct pregnant women to use appropriate contraception during and within a certain period of time after administration.

2. Pregnant women: Do not give this medicine to pregnant women or women who may become pregnant. Fetal toxicity has been reported in animal experiments. In an experiment in which morphinepilavir was administered to pregnant rats during organ development, it was found that the dose for fetal growth retardation was 8 times the clinical exposure of N-hydroxycytidine (NHC), and the dose for teratogenesis and embryolethality was more than 3 times.

3. Breastfeeding women: Considering the benefits of treatment and the benefits of breast milk nutrition, consider continuing or stopping breastfeeding. No milk migration test of morphinepiravir has been conducted in animals, and there is no data on whether it migrates into human milk and its effects on milk.

4. Children, etc.: No clinical trials have been conducted on subjects under the age of 18.

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