来法莫林(Xenleta)的副作用和不良反应

In addition to its intended therapeutic effects, Xenleta may cause some adverse effects. Although not all of these side effects will occur, if they do, they may require medical attention.

Side effects of Xenleta that require immediate medical attention

Less common side effects

Seizures, decreased urine output, dry mouth, increased thirst, irregular heartbeat, loss of appetite, mood changes, muscle pain or cramps, nausea or vomiting, numbness or tingling in the hands/feet or lips, difficulty breathing, and unusual tiredness or weakness may occur.

Side effects of unknown frequency may also occur.

Other side effects of Xenleta

Some side effects may occur that usually do not require medical attention. These side effects may go away during treatment as your body adjusts to the medication. Additionally, your medical professional may be able to tell you how to prevent or reduce some side effects.

The pictures come from public channels (such as the official website of the FDA, the official website of the original drug manufacturer, etc.) and are for reference only.

Side effects of Xenleta that require immediate consultation with your doctor

Less common side effects

Including headache and difficulty sleeping (insomnia).

Side Effect Management for Medical Professionals

1. Gastrointestinal adverse events

(1), very common (10% or more): diarrhea (up to 12%).

(2). Common (1% to 10%): nausea and vomiting.

(3) Reported but unknown frequency include: abdominal pain, constipation, dyspepsia, epigastric discomfort, erosive gastritis, Clostridium difficile-associated diarrhea, Clostridium difficile colitis, and oropharyngeal candidiasis.

2. Local reaction

Common (1% to 10%): administration site reaction (including infusion site pain, infusion site phlebitis, injection site reaction).

3. Hepatobiliary system

(1), common (1% to 10%): elevated liver enzymes (including elevated ALT, elevated AST, elevated liver function tests).

(2). Things that have been reported but with unknown frequency include: elevated GGT.

4. Metabolic system

Common (1% to 10%): hypokalemia.

5. Mental system

(1). Common (1% to 10%): insomnia.

(2). Things that have been reported but with unknown frequency include: anxiety.

6. Nervous system

(1) Common (1% to 10%): headache.

(2). Reported but unknown frequency includes: drowsiness.

7. Other side effects

(1) Common (1% to 10%): death within 28 days.

(2). Reports that have been reported but with unknown frequency include: elevated alkaline phosphatase.

8. Cardiovascular system

Reports that have been reported but with unknown frequency include: atrial fibrillation, palpitations, and prolongation of the QT interval in the electrocardiogram.

9. Genitourinary system

Vulvovaginal candidiasis and urinary retention have been reported but the frequency is unknown.

10. Blood system

Things that have been reported but with unknown frequency include: anemia and thrombocytopenia.

11. Musculoskeletal system

Things that have been reported but with unknown frequency include: elevated creatine phosphokinase.

The above content only reflects the range of side effects of Xenleta in overseas registered countries, and does not represent the approved range of use in mainland China. Please do not make any treatment decisions based on this.