噻托溴铵奥达特罗能倍乐多久有效果

Tiotropium bromide and olodaterol are long-acting anticholinergic drugs that have selective inhibitory effects on M3 receptors. They have the advantages of long blood concentration maintenance and minimal side effects. It should be noted that tiotropium bromide and olodaterol and Respimat are contraindicated in patients with allergic reactions to tiotropium bromide, atropine or their derivatives, such as ipratropium bromide or oxotropium bromide or the excipient lactose of this product.

In the human airway, tiotropium bromide, olodaterol, and repimat have a high affinity for receptors and dissociate slowly from muscarinic M1 and M3 receptors, which can block cholinergic nerve-mediated contraction of bronchial smooth muscle for a long time. However, tiotropium bromide, olodaterol, and repimat dissociate from muscarinic M2 receptors quite quickly, thus showing unique kinetic selectivity for M1 and M3 receptors.

In a research trial, 298 patients with chronic obstructive pulmonary disease were included and randomly divided into an observation group (149 cases) and a control group (149 cases). The observation group was treated with tiotropium bromide, olodaterol, and repimat for 3 months, and the control group was treated with aminophylline for 3 months. The results showed that the lung function increase index of patients treated with tiotropium bromide, olodaterol, and repimat was significantly better than that of the control group, and the difference was statistically significant. In terms of the incidence of adverse reactions, the incidence rate in the tiotropium bromide olodaterol and repimat treatment group was 3.3%, and that in the control group was 10.7%. The difference between the two groups was statistically significant. Treatment of patients with tiotropium bromide, olodaterol, and repimat can effectively improve lung function indicators with significant results.

The above is an introduction to the effect of tiotropium bromide and olodaterol in the treatment of chronic obstructive pulmonary disease. During the treatment period, patients should strictly follow the doctor's instructions and use the medicine correctly, so as to ensure the effective effectiveness of the medicine.

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