能倍乐 思力华噻托溴铵的使用说明书
Instructions for use of Tiotropium bromide
Drug introduction: Respimat, Slivar, and tiotropium bromide are long-acting anticholinergic drugs that have selective inhibitory effects on M3 receptors. They have the advantages of long maintenance of blood concentration and minimal side effects. In human airways, Respimat has a high affinity for receptors and dissociates slowly from muscarinic M1 and M3 receptors, and can block cholinergic nerve-mediated contraction of bronchial smooth muscle for a long time. However, Respimat dissociates from the muscarinic M2 receptor quite quickly, thus showing unique kinetic selectivity for M1 and M3 receptors.
Product name: Spiriva Respimat
Main ingredients: tiotropium bromide
Indications: It is suitable for the maintenance treatment of chronic obstructive pulmonary disease (COPD, including chronic bronchitis and emphysema) and related dyspnea. It can improve the quality of life of COPD patients and reduce acute exacerbations of COPD.
Usage and Dosage: Respimat can only be used by inhalation. Bottles containing tiotropium bromide may only be used by inserting the Respimat inhalation device and inhaling it through the Respimat inhalation device. The recommended dose for adults is 2 puffs taken once daily via the Respimat inhaler device at the same time. Patients should not overdose.
Adverse reactions: Common adverse reactions are dry mouth (3.2%), and serious adverse reactions include glaucoma, constipation, intestinal obstruction including paralytic ileus, urinary retention, etc.
Precautions: 1. Do not use if you are allergic to tiotropium bromide or olodaterol or any other component of this medicine. It should not be used if you are allergic to atropine or substances related to it, such as ipratropine or oxytropine.
2. Like other anticholinergic drugs, it should be used with caution in patients with narrow-angle glaucoma, prostatic hyperplasia, or bladder neck obstruction.
3. Tiotropium bromide should not be used as the initial treatment for acute attacks of bronchospasm, that is, as a rescue drug.
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