罗氟司特治疗慢性阻塞性肺病时能起到什么治疗作用？

Chronic obstructive pulmonary disease is a very common respiratory disease that occurs mainly due to long-term damage to lung tissue. This disease often occurs in smokers. Patients with chronic obstructive pulmonary disease often experience symptoms such as shortness of breath, chest tightness, and coughing and sputum. If the patient does not receive timely diagnosis and treatment, once the disease progresses, it will eventually lead to complications such as heart failure and emphysema. Therefore, patients with chronic obstructive pulmonary disease must take reasonable drugs for treatment, such as roflumilast, under the guidance and advice of doctors. So, what role does this drug play in treating chronic obstructive pulmonary disease? Let’s take a look together!

What therapeutic role does roflumilast play in the treatment of chronic obstructive pulmonary disease?

Roflumilast is a long-acting inhibitor of selective phosphodiesterase type 4 (PDE-4) and has anti-inflammatory effects. Phosphodiesterases are a family of enzymes including at least 11 subtypes of enzymes that catalyze the decomposition of the messenger molecules cyclic adenosine monophosphate and/or cyclic guanosine monophosphate. Phosphodiesterase-4 is a major cyclic adenosine monophosphate metabolic enzyme in inflammatory and immune cells, and phosphodiesterase-4 inhibitors have broad anti-inflammatory activities including inhibiting the release of inflammatory mediators and inhibiting immune cell activation. In addition, phosphodiesterase-4 inhibitors have also been shown to have therapeutic effects in animal models of airway inflammation.

Judging from the above content, roflumilast can play a very good therapeutic role in the treatment of chronic obstructive pulmonary disease! If you need to purchase the drug Roflumilast, please contact the Medical Companion Travel Service.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.