Budenofalk可治疗什么病症?
What conditions can be treated? Budenofalk is an adrenal glucocorticoid, available as inhalers, pills, intranasal sprays, and anal plugs. Inhaled dosage forms can be used to treat asthma and chronic obstructive pulmonary disease with long-term use. Nasal sprays are used to treat allergic rhinitis and nasal polyps. Extended-release anal plugs are used to treat inflammatory bowel diseases such as Crohn's disease, ulcerative colitis, and minimally invasive colitis. Common side effects of the tablet form include fatigue, vomiting, and joint pain.
Budenofalk is a halogen-free, topical glucocorticoid that is currently one of the most commonly used drugs for the treatment of asthma in various countries around the world. Budenofalk has a strong local anti-inflammatory effect, and its mechanism may be: enhancing the stability of mast cells and lysosomal membranes, reducing degranulation and the release of lysosomal enzymes; anti-immune effects, inhibiting inflammation caused by immune responses, etc.; for patients with airway hyperresponsiveness, Budenofalk can significantly reduce the airway response to histamine and methacholine. About 10% of the aerosol is deposited in the lung tissue after inhalation. About 90% of the swallowed residual drugs are rapidly metabolized by the liver and inactivated.
Budenofalk is a locally acting, non-systemic corticosteroid. The dosage form is a new oral tablet made using the patented technology of MMX multi-matrix system. Take budesonide about half an hour before meals and swallow it whole with a large amount of liquid (such as a glass of water). Treatment to maintain remission in autoimmune hepatitis (adults over 18 years of age) should be continued for at least 24 months. Its termination is possible only if biochemical remission is sustained and signs of inflammation are absent in liver biopsy. Termination of treatment: It should not be stopped suddenly but gradually withdrawn (tapered). During the first week, the daily dose should be reduced to two capsules, one in the evening and one at night. During the second week, take only one capsule in the morning. Treatment can then be stopped.
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