布地奈德治疗哮喘效果如何？

It is a glucocorticoid with highly effective local anti-inflammatory effects. It can enhance the stability of endothelial cells, smooth muscle cells and lysosomal membranes, inhibit immune responses and reduce antibody synthesis, thereby reducing the release and activity of allergic active mediators such as histamine. It can also reduce the enzymatic process triggered when antigens and antibodies are combined, inhibit the synthesis and release of bronchoconstrictive substances and reduce the contractile response of smooth muscles. Budesonide has a strong local anti-inflammatory effect and is one of the important drugs for the treatment of allergic asthma. Budesonide has a long-lasting effect and has no systemic adrenocortical hormone effect. It is more suitable for topical administration. It is a first-line drug for the treatment of asthma by aerosol inhalation and spray in the nasal cavity for the treatment of allergic reactions. Clinical studies have found that the systemic effects of budesonide, such as weight loss, lymphoid tissue and adrenal cortex atrophy, are weaker than or equivalent to other glucocorticoids. After systematic evaluation in six different experimental tests, budesonide has no mutagenic or carcinogenic effects.

How effective is budesonide in treating asthma?

The clinical trial selected 85 patients with bronchial asthma who received treatment and divided them into an experimental group of 43 patients and a control group of 42 patients using the random number table method. Patients in the control group were treated with albuterol sulfate, and patients in the experimental group were treated with budesonide. After 2 weeks, the treatment effects and incidence of adverse reactions were compared. Clinical trial results showed that the therapeutic efficacy rate of patients in the budesonide group was 95.35%, which was significantly higher than the 69.05% in the control group, and the difference was statistically significant. No patients in the two groups experienced serious adverse reactions. The incidence of adverse reactions in the budesonide group was significantly lower than that in the control group, and the difference was statistically significant.

It has significant efficacy and high safety when used in bronchial asthma. However, budesonide is not yet available in China. A box of 100 pills of budesonide available in Turkey costs about $800. For details, please consult overseas medical service organizations (such as Medical Companion Travel).