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布地奈德治疗哮喘的效果如何?

Author: Medicalhalo
Release time: 2025-10-19 11:44:20

How effective is (Budesonide, Budenofalk) in treating asthma? Let’s take a look at it together. The manufacturer of budesonide has high partial glucocorticoid (GCS) activity and substantial first-pass elimination. This formulation contains budesonide in an extended-release tablet core. Tabletcore's enteric coating protects its dissolution in gastric juices, thereby delaying the release of budesonide until the pH of the small intestine is ≥7. The core matrix provides prolonged release of budesonide in a moment-dependent manner upon disintegration of the coating. Budesonide is an anti-inflammatory corticosteroid with high glucocorticoid effects and weak mineralocorticoid effects. Budesonide's affinity for the glucocorticoid receptor, which reflects the intrinsic potency of the drug, is 200 times that of cortisol and 15 times that of cortisol. Budesonide is indicated for chronic reversible airway obstructive diseases such as bronchial asthma.

The clinical trial selected 85 patients with bronchial asthma who received treatment and divided them into an experimental group of 43 patients and a control group of 42 patients using the random number table method. Patients in the control group were treated with albuterol sulfate, and patients in the experimental group were treated with budesonide. After 2 weeks, the treatment effects and incidence of adverse reactions were compared. Results: The treatment effectiveness rate of patients in the experimental group was 95.35%, which was significantly higher than the 69.05% in the control group, and the difference was statistically significant (P=0.05). No patients in the two groups experienced serious adverse reactions. The incidence of adverse reactions in the experimental group was significantly lower than that in the control group, and the difference was statistically significant (P=0.05). Conclusion Budesonide has significant efficacy and high safety when used in bronchial asthma.

The above is the treatment effect of Budesonide provided by our medical companion travel overseas medical consulting service company. From this point of view, the effect of (Budesonide) is still very good.

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