Budesonide怎么使用？

How to use budesonide ()?布地奈德（Budesonide）是一具有高效局部抗炎作用的糖皮质激素。 It can enhance the stability of endothelial cells, smooth muscle cells and lysosomal membranes, inhibit immune responses and reduce antibody synthesis, thereby reducing the release and activity of allergic active mediators such as histamine. It can also reduce the enzymatic process triggered when antigens and antibodies are combined, inhibit the synthesis and release of bronchoconstrictive substances and reduce the contractile response of smooth muscles.

The dose of Budesonide nasal spray should be individualized for rhinitis: the recommended starting dose for adults and children over 6 years old is 256ug per day. This dose can be sprayed once in the morning or twice in the morning and evening.即：早晨每个鼻孔内喷入128ug（2*64ug）；或早晚两次，每次每个鼻孔内喷入64ug。 No increase in effect was seen when the daily dose exceeded 256ug. After the desired clinical effect is achieved, reduce dosage to the low doses needed to control symptoms. Clinical trials have shown that some patients spraying 32ug into each nostril every morning as a maintenance dose is sufficient. Some patients experience relief of symptoms 5-7 hours after starting treatment. Full effects may be achieved after several days of treatment (2 weeks in a few patients). Therefore, treatment of seasonal rhinitis is best initiated before allergen exposure, if possible. Severe nasal congestion may require the use of vasoconstrictor drugs. Adjuvant treatments may sometimes be needed to control eye symptoms caused by allergies.

Treatment or prevention of nasal polyps: The recommended dose of Budesonide is 256ug per day. This dose can be sprayed once in the morning or twice in the morning and evening. After obtaining the desired effect, reduce the dosage to the minimum dose that controls symptoms as a maintenance dose. For the treatment of allergic rhinitis in adults aged 18 years and older, a 32 μg spray dose does not require a prescription. Budesonide (Budesonide) can be used for up to 3 months.