达利雷生(Quviviq)能有效治病吗？

Introduction: Quviviq was developed by the Swiss biopharmaceutical company Idorsia Pharmaceuticals. It is a new treatment and will be launched in the United States in May 2022. Quviviq binds to the OX1R and OX2R orexin receptors and inhibits their binding to the wakefulness-promoting neuropeptides orexin A and orexin B, which are thought to inhibit wakefulness drive.

Can the generic version of Quviviq also be effective in treating diseases?

It is a new anti-insomnia drug that has been approved by the US FDA for the treatment of adult patients with insomnia. It has also completed Phase III clinical studies in China, showing good efficacy and safety. However, as of now, we are not aware that there is a generic version of Quviviq on the market, so we cannot know its efficacy.

Generic drugs are drugs approved by regulatory agencies after the patent of the original drug expires, and have the same active ingredients, dosage form, route of administration and therapeutic effect as the original drug. Generic drugs need to pass bioequivalence testing to prove that there is no significant difference in efficacy and safety from the original drug. If a generic drug of Quviviq is launched in the future, it means that it has been approved by the relevant regulatory authorities, and its drug ingredients and efficacy are basically the same as the original drug, and it can also effectively treat diseases.

What is the therapeutic effect of Quviviq?

In clinical studies, Quviviq has shown positive effects. After receiving Quviviq for 1 month and 3 months of treatment, compared with placebo, it significantly improved the patient's sleep onset, sleep maintenance, and self-reported total sleep time, without changing the sleep structure. In addition, no evidence of dependence, rebound insomnia, withdrawal symptoms, or drug abuse was found in the study, which shows clear advantages compared with traditional sedative-hypnotic drugs (such as benzodiazepines).

In general, DaliRasen has shown good efficacy and safety in the treatment of insomnia, but it may vary due to individual differences, so you should consult a doctor before use and perform treatment under the guidance of a doctor.

Precautions for Quviviq

1. Quviviq may aggravate depression and trigger suicidal thoughts and behaviors. If you find that your depression is worsening or you have thoughts of harming yourself, it is recommended to inform your doctor immediately.

2. DaliRasen can cause sleep paralysis, which is the inability to move or speak within a few minutes of falling asleep or waking up, and may also cause hallucinations.

3. DaliRasen can cause abnormal sleep behavior, which may cause patients to engage in various activities during sleep, such as sleepwalking, sleepwalking driving, eating, and talking on the phone. If any sleep behavior occurs, you should stop taking DaliRasen and contact your doctor for treatment.