莱博雷生在中国上市了吗？如何购买？

Leborexan is a new dual orexin receptor antagonist in the field of insomnia treatment. Its accessibility and usage regulations in the Chinese market have attracted much attention. The drug works by precisely regulating the sleep-wake cycle. Its marketing status, legal access and core functions form the basis for patients' medication decisions. This article will systematically elaborate on the launch progress in China, purchase channels and drug action mechanism.

Is Lebraxanthin available on the market in China?

It has passed the priority review process of the National Medical Products Administration (NMPA) of China. The application for the domestic marketing of Lebraxanthin tablets has been accepted, but it has not yet been officially launched in mainland China.

Approval Process and Scope of Application

Lebraxant has been launched in Hong Kong, China. Two specifications of Lebraxant, 2.5mg and 5mg, have been approved for marketing. The 10mg high-dose version is still undergoing supplementary clinical trials. The approved indication is clearly limited to chronic insomnia in adults, requiring patients with a disease duration of more than 3 months and sleep disturbance at least 3 times a week.

Domestic supply and medical insurance coverage

The first batch of marketed drugs are sub-packaged and produced by Suzhou Eisai Pharmaceuticals, using the same raw materials and formulation processes as the original drugs. It has not been included in the national medical insurance catalog yet, and patients need to purchase the medicine at their own expense.

How to purchase Laibo Leisheng

Laibo Leisheng needs to be purchased with an electronic or paper prescription issued by a licensed physician, and the online drug purchase platform must have Internet hospital qualifications.

Hospital and physical pharmacy channels

In the activity area of ​​listed countries, patients can directly pick up the medicine at the hospital pharmacy after visiting the sleep specialist outpatient clinic of the hospital. The medicine can also be purchased in some chain pharmacies. Before purchasing the medicine, the original doctor's prescription and identification must be presented.

Internet medical platform

Patients can also complete the entire process of online consultation-electronic prescription-drug delivery through the Internet compliance platform. The platform requires sleep monitoring reports or past medication records from offline hospitals within 6 months.

The role and efficacy of lebraxen

Lebraxen inhibits the arousal signaling pathway by selectively blocking the hypothalamic orexin receptors OX1R and OX2R. Its half-life is about 17 hours, and it can simultaneously improve difficulty in falling asleep and maintaining sleep. The residual effect the next day is significantly lower than that of benzodiazepines.

Analysis of the core mechanism of action

The drug has a high permeability through the blood-brain barrier. It inhibits the activity of arousal neurons in the lateral hypothalamus and prolongs the N3 stage of non-rapid eye movement sleep. Phase III clinical trials show that after 4 weeks of continuous use, the patient's subjective sleep quality score improved and the sleep latency was shortened to .

Leborexen is an insomnia treatment drug and its use must be strictly followed as directed by your doctor. Patients should fully understand drug usage, precautions, etc. before receiving treatment, and maintain close communication with their doctors during the treatment process in order to promptly adjust the treatment plan and respond to possible problems.