对于舍曲林这个药物,你了解的真的够多吗？

Adolescent depression is a common mental illness. In addition to typical characteristics such as low mood and lack of fun, non-suicidal self-injurious behavior is also a common clinical manifestation. Non-suicidal self-injury (NSSI) refers to the behavior of injuring one's own body without intending to die. The main manifestations include cutting, burning, acupuncture or friction. Patients in this type have more negative emotional experiences, avoidance behaviors, and poorer ability to manage impulsive emotions and behaviors. Hydrochloric acid tablets were developed by Pfizer and launched in the UK in 1990. Since its launch, it has been among the top five prescription antidepressants in the world and has proven clinical efficacy in treating depression.

Sertraline will increase the level of 5-hydroxytryptamine in the synaptic cleft and promote its combination with 5-hydroxytryptamine receptors, inhibit the excitement of the central sympathetic nerve, reduce the release of CA, slow down the heart rate and reduce myocardial oxygen consumption, relieve fear, anxiety and other emotions, inhibit the activity of sympathetic nerves and reduce the body's CA content, relieve depression; it can also act on platelets, reduce platelet activity, and affect platelet adsorption, aggregation, secretion and other functions.

Studies have shown that sertraline can enhance the transmission function of serotonin in the central system of patients with epilepsy and depression, and can effectively reduce the patient's mental symptoms in a short period of time. The results of the study showed that after treatment, the HAMD score of the patients in the observation group was lower than that of the control group; the cognitive domain, drug impact, social function, energy/fatigue, mood, life satisfaction, seizure worry, and total score of the QOLIE31 scale were all higher than those of the control group. It can be seen that the combination of levetiracetam and sertraline in patients with epilepsy and depression can effectively reduce patients' depressive symptoms and improve their quality of life.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.