唑来膦酸有什么危害？唑来膦酸的说明书

The main pharmacological effect of Zoledronic Acid is to inhibit bone resorption. Zoledronic acid can inhibit osteoclast activity and induce osteoclast apoptosis in vitro. What's the harm? Next, let’s take a look at the instructions for zoledronic acid.

【Indications】

Zoledronic acid is suitable for the treatment of pain caused by osteolytic bone metastasis of malignant tumors.

【Usage and Dosage】

Zoledronic acid requires intravenous infusion. For adults, 4 mg each time, Zoledronic Acid should be diluted with 100 ml of 0.9% sodium chloride injection or 5% glucose injection and then infused intravenously. The infusion time should be no less than 15 minutes. Administer every 3-4 weeks or as directed by your doctor.

【Hazard】

Symptoms such as fatigue, chest pain, swollen feet, conjunctivitis, nausea, vomiting, constipation, diarrhea, abdominal pain, difficulty swallowing, and anorexia may occur when receiving zoledronic acid treatment. Patients with more serious conditions should seek medical treatment immediately and seek help from a doctor, and should not use medication without authorization.

【Notes】

If renal function worsens while receiving Zoledronic Acid, Zoledronic Acid should be discontinued until renal function returns to baseline.

This medicine should not be used in patients who are allergic to Zoledronic Acid or other bisphosphonates.

Treatment with Zoledronic Acid is not recommended for patients with severe renal insufficiency.

It is not clear whether Zoledronic Acid will be excreted into breast milk. Because Zoledronic Acid can bind to bones for a long time, it is contraindicated in pregnant and lactating women.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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