Naldemedine(纳地美定)用法用量是怎样的？

What is the dosage of Naldemedine?

Constipation caused by opioids may occur rapidly within a few days and lead to serious complications. Naldemedine is an opioid antagonist that is mainly used for patients with constipation caused by opioids. It solves the constipation condition without affecting the analgesic effect of cancer patients and can improve the quality of life of cancer patients.

Naldemedine is an oral drug. The recommended dosage in the instructions is 0.2 mg orally administered once a day. It can be taken with or without food. Naldemedine was developed by Japan's Shionogi. The specification is 0.2mg*50 tablets, which means patients only need to take one tablet a day.

The efficacy of Naldemedine in practical application

Naldemedine has been marketed in Europe, the United States and Taiwan, China. At the Boao Research Hospital in Hainan, Professor Wang Lin’s team prescribed the first clinical prescription of Naldemedine tablets in China for a patient with cancer pain and constipation, and provided on-site medication guidance. The patient felt good after receiving the new drug treatment. After a follow-up visit one week later, the patient reported that he could defecate normally and voluntarily after taking the medicine, the bloating feeling disappeared, the constipation symptoms were completely improved, and the medicine was effective.

Naldemedine can fundamentally treat constipation in patients with opioid-related constipation (OIC) by antagonizing the physiological effects of opioids on the enteric nervous system in peripheral tissues (especially the enteric nervous system), regulating intestinal peristalsis and secretory activities. Professor Wang Lin said: After successfully landing in Lecheng, it can provide a very effective treatment method for patients with constipation caused by taking opioids in mainland China.

At present, Naldemedine has not been officially launched in mainland China. You can obtain this product that is available overseas through domestic professional overseas medical service institutions. It can be directly mailed to your home from overseas, ensuring that the drug is genuine and affordable. It is recommended to consult the customer service staff for specific costs and drug purchase procedures, so that drug purchase is guaranteed.

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