氯替泼诺混悬滴眼液(Lotemax)的用法用量

Loteprednol Suspension Eye Drops (Lotemax) is a corticosteroid preparation containing 0.5% loteprednol etabonate.

Loteprednol Suspension Eye Drops (Lotemax) Usage and Dosage

1. Treatment of steroid-sensitive diseases

Instill one to two drops of Loteprednol Suspension Eye Drops into the conjunctival sac of the affected eye four times a day. The dose can be gradually increased to one drop per hour during the first week as needed for treatment.

Care should be taken to avoid premature discontinuation of treatment, and patients should be re-evaluated if their signs and symptoms do not improve after two days.

2. Prevention and treatment of postoperative inflammation

Starting 24 hours after surgery, instill one to two drops of loteprednol suspension eye drops (Lotemax) into the conjunctival sac of the operated eye four times a day, and continue throughout the first two weeks of the postoperative period.

3. Administration method

Be sure to wash your hands before use.

4. Treatment course

Start 24 hours after surgery and continue throughout the first two weeks of the postoperative period.

5. Important precautions

(1) Loteprednol suspension eye drops (Lotemax) are topical ophthalmic preparations and are strictly prohibited for intraocular injection.

(2). Do not touch the mouth of the tube to the eyelids or surrounding areas. Cap the bottle tightly after use to avoid contamination.

(3). Contact lenses are not allowed during treatment.

(4). If symptoms and signs do not improve after 2 days of medication, you should seek medical re-evaluation.

The pictures come from public channels (such as the official website of the FDA, the official website of the original drug manufacturer, etc.) and are for reference only.

Loteprednol Suspension Eye Drops (Lotemax) Medication for Special Populations

1. Pregnant women

There are no sufficient and well-controlled studies on pregnant women.

Animal experiments have shown that oral loteprednol is teratogenic in rabbits and rats at clinically relevant doses. This product should be used during pregnancy only if the potential benefit outweighs the potential risk to the fetus.

2. Breastfeeding women

It is unclear whether loteprednol will be excreted into human milk after topical eye medication, and whether it will affect breastfed infants or milk production.

The decision whether to stop breastfeeding or discontinue medication should be made carefully, taking into account the developmental and health benefits of breastfeeding, the mother's clinical need for this product, and any potential adverse reactions of this product to the infant.

3. Medication in children

So far, the safety and effectiveness of loteprednol suspension eye drops for pediatric patients have not been fully established.

4. Medication for the elderly

Through long-term follow-up observations of elderly patients and young adult patients, no overall difference in safety and effectiveness has been found.

5. Patients with hepatic and renal insufficiency

The instructions do not provide specific guidance. Since the systemic absorption of Loteprednol Suspension Eye Drops is very small, there is usually no need to adjust the dose, but it is still recommended to be used under the guidance of a doctor.

6. Patients with glaucoma

Such patients should use corticosteroids with caution. If loteprednol suspension eye drops are used for more than 10 days, intraocular pressure (IOP) should be monitored.