万赛维效果好吗？

(Valcyte) is an oral anti-cytomegalovirus infection drug developed by the Swiss company Roche. It was approved by the US FDA in May 2001. Valcyte is clinically used to treat acute retinitis caused by CMV infection in patients with acquired immunodeficiency syndrome. In May 2003, its indications were expanded. Valcyte is used to prevent and treat secondary CMV infection in organ transplant recipients.

Is Vansavi effective?

Clinical studies of Valcyte in AIDS patients infected with CMV retinitis have shown that valganciclovir hydrochloride tablets and intravenous ganciclovir are equally effective in the induction treatment of CMV retinitis. In the study, patients with newly diagnosed CMV retinitis were randomly assigned to the Valcyte group or the intravenous ganciclovir group for induction therapy. The proportion of patients with progression of CMV retinitis at week 4 was the same in both groups. After induction therapy, both groups of patients in the study continued to receive maintenance therapy with Valcyte 900 mg daily. Among patients who received induction therapy with Valcyte or intravenous ganciclovir followed by maintenance therapy with valganciclovir hydrochloride tablets, the mean (median) time from randomization to progression of CMV retinitis was: 226 (160) days and 219 (125) days.

Common adverse reactions in the study include: gastrointestinal disorders: abdominal distension, cholangitis, dyspepsia, dysphagia, hiccups, esophagitis, fecal incontinence, flatulence, gastritis, gastrointestinal disorders, gastrointestinal bleeding, oral ulcers, pancreatitis, and tongue dysfunction. Systemic: ascites, asthenia, bacterial, fungal and viral infections, bleeding, malaise, mucosal disease, pain, photosensitivity, chills, sepsis. Liver disorders: hepatitis, jaundice. Skin and appendages: Acne, alopecia, seborrheic dermatitis, dry skin, increased sweating, urticaria.

Contraindications: Valganciclovir Hydrochloride Tablets should not be used in patients with a known allergic reaction to valganciclovir, ganciclovir, or any other ingredient in the drug. Due to the similar chemical structure of the tablets to aciclovir and valaciclovir, there may be a cross-allergic reaction between these drugs.