Can Amivantamab effectively treat the disease?

Introduction: In March 2024, the FDA approved the first-line drug amivantamab in combination with carboplatin and pemetrexed for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) carrying EGFR exon 20 insertion mutations.

Can the generic version of Amivantamab also be effective in treating the disease?

Amivantamab is a bispecific antibody that targets EGFR and c-Met and is used to treat certain types of non-small cell lung cancer. Normally, generic drugs need to be proven to be equivalent in efficacy, safety and quality to the original drug through bioequivalence studies after the patent of the original drug expires before they can be considered effective. However, there are currently no direct search results showing that there are generic versions of evantuzumab on the market, so it is impossible to judge the effectiveness of generic versions of evantuzumab.

Evantumumab is a newer treatment and its patent may still be valid, so there may not yet be an officially approved generic version on the market. If unapproved generic drugs exist, their quality and efficacy may not be guaranteed, and there are risks in using such generic drugs.

When considering using generic drugs, patients should consult their doctors or medical professionals and ensure that they come from reliable sources and are legally approved and regulated. In addition, patients should pay attention to the drug's manufacturer, approval number, production date and other information to ensure the safety and effectiveness of the drug.

How to identify the authenticity of evantumumab

To identify the authenticity of evantumumab, you can refer to the following steps.

1. Check the drug packaging: The packaging of genuine evantumumab should be intact and contain comprehensive information such as drug name, ingredients, indications, usage and dosage, production batch number, expiration date, manufacturer, etc., and the information on the packaging should be clear and readable, with no spelling errors or ambiguities.

2. Understand the source of the drug: Understand the purchasing channels of evantumumab. Drugs purchased through formal channels are more likely to be genuine.

3. Consult a professional doctor or pharmacist: Before using evantumumab, you can consult a doctor or pharmacist. They can provide professional advice and help identify the authenticity of the drug.

4. Pay attention to the price: If the price of evantumumab is found to be unusually low, much lower than the market price, it may be a sign of counterfeit and substandard drugs.

The above suggestions are for reference only. The more reliable way to identify the authenticity of drugs is to purchase them through formal channels and consult professional medical personnel before use.

Amivantamab side effects

As the body gradually adapts to Amivantamab, the side effects may gradually get better.

1. Common side effects: including rash, infusion reaction, shortness of breath, nausea, fatigue, swelling, oral ulcers, cough, constipation, vomiting, etc.

2. Other side effects: including bleeding, itching, dry skin, diarrhea, stomach pain, loss of appetite, nerve pain, headache, etc.

3. Serious side effects: mainly including infusion reactions, lung damage, severe skin reactions, eye problems, etc.

If continue to occur, or symptoms worsen over time, you need to inform your doctor immediately for appropriate treatment.