培美替尼在国内买的到吗?多少钱一盒?纳入医保了吗?
Pemetinib is a selective fibroblast growth factor receptor (FGFR) kinase inhibitor that blocks the growth and spread of tumor cells by blocking FGFR2 in tumor cells. Pemetinib is a small molecule kinase inhibitor. The mean values of the 50% maximum inhibitory concentration (MIC50) for selectively inhibiting FCFR1, FGFR2 and FGFR3 are 0.4, 0.5 and 1.0 nmol·L-1 respectively. For the less active FGFR4, the mean value of the 50% maximum inhibitory concentration (IC50) is 30 nmol·L-1. Various non-FCFR receptor kinases, including vascular endothelial growth factor receptor 2 and inserted domain tumor xenograft models, have IC50 ≥ 182 nmol·L-1. The IC50 of inhibiting the autophosphorylation of FGFR in vitro is 22 nmol·L-1. In the tumor xenograft model, the IC50 of pemetinib inhibiting the autophosphorylation of FCFR2 in plasma is 22 nmol·L-1.
Is pemetinib available in China? How much does a box cost? Is it covered by medical insurance? Pemetinib has not been approved for sale in China, and it has not yet been included in the national medical insurance to provide everyone with preferential policies. This means that patients will not be able to buy pemetinib at all in the country. Faced with this situation, more patients choose to go to distant overseas countries to purchase medicines under huge financial pressure. However, this method costs a lot of manpower, material resources and financial resources, which is miserable. However, according to Medical Companion Travel, the pemetinib version is very cost-effective and has been well received by many patients. The specification is 13.5mgx14 tablets and the price is about 341,175$. However, because the price of the drug rises and falls with the fluctuation of the exchange rate in the market, the specific price of the drug is not stable. For more information about pemetinib, please contact Medical Travel for details.
Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.
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