培美替尼2021年6月价格?培美替尼正品哪里买?
Pemetinib is a kinase inhibitor indicated for adults with previously treated, unresectable locally advanced or metastatic cholangiocarcinoma with fibroblast growth factor receptor 2 (FGFR2) fusions or other rearrangements as detected by an FDA-approved test. Pemetinib is a small molecule kinase inhibitor targeting FGFR1, 2, and 3, with an IC50 value of less than 2 nM. Pemetinib also inhibits FGFR4 in vitro at a concentration that is approximately 100 times higher than that of FGFR1, 2, and 3. Pemetinib leads to constitutive activation of FGFR by activating FGFR amplification and fusion, thereby inhibiting FGFR1-3 phosphorylation and signaling and reducing cell viability. Constitutive FGFR signaling can support the proliferation and survival of malignant cells. Demonstrated antitumor activity in a mouse xenograft model of human tumors harboring alterations in FGFR1, FGFR2, or FGFR3, resulting in constitutive FGFR activation, including cholangiocarcinoma xenograft models in patients expressing an oncogenic FGFR2-Transformer-2 beta homolog (TRA2b) fusion protein.
Pemetinib price in June 2021? Where to buy genuine Pemetinib? Pemetinib is currently not approved for marketing in China. Drugs that are not on the market have no way to enter the national medical insurance. Patients who want to use this drug have the only way to purchase drugs abroad. However, the manpower, material and financial resources consumed by purchasing drugs overseas are far beyond imagination, which gives many patients a headache. According to Medical Travel, the Indian version of pemetinib is more affordable and does not require you to travel between domestic and foreign countries. The drug purchase method is overseas direct mail. In addition to being affordable, the drug can be delivered directly to you conveniently and quickly, which is very worry-free and labor-saving. Since the market price of the drug changes closely with the fluctuation of the exchange rate, the specific price is not static. If you want to know more about pemetinib, please contact Medical Travel for details.
Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.
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