英菲格拉替尼国内怎么购买？治疗效果好不好？

Infigratinib blocks downstream signaling cascades by selectively binding and inhibiting FGFR activity. The drug is a small molecule ATP-competitive tyrosine kinase inhibitor of FGFR. It is mainly used to treat cholangiocarcinoma with significant results. The drug will be launched in the United States in 2020. So, how to buy it in China? Is the treatment effective?

Infigratinib is not yet on the market in China, so patients can only go abroad to purchase the drug. However, the financial burden will be heavier, and the real drug may not be available. Purchasing through a purchasing agent is too risky and is not suitable for long-term medication use by patients. The editor recommends that patients obtain drugs through medical companion travel. They can buy the overseas version of Infigratinib without going abroad. The price is affordable and cost-effective, and it can also guarantee that the drug is genuine. Obtaining medicines through medical companion travel is favored by many domestic patients and is a relatively reliable channel for purchasing medicines. Since this product is not on the market in China, the price of the drug cannot be found yet. Patients can also consult the medical companion passenger service staff about the price of the overseas version of Infigratinib in 2021, including the drug purchase process and more details, which can also be answered by patients.

In a clinical study on infigratinib, as a third-line or above treatment for patients with FGFR2 fusion-positive cholangiocarcinoma, the median PFS of patients treated with infigratinib was 4.63 months, which was the result of its use as a second-line drug; the median PFS of patients treated with infigratinib as a third-line or above treatment was 6.77 months. It can be seen that this drug has great benefits in both PFS and ORR. In terms of safety, stomatitis, alopecia, hyperphosphatemia, fatigue, constipation, dry eye syndrome and taste disorder are its main adverse reactions.

It is good for patients to use it, but it should be noted that before taking the drug, it is necessary to determine whether there is FGFR2 gene fusion or rearrangement. This product is taken orally once a day, and the recommended dose is 125 mg. A treatment cycle is 28 days, with 21 days of continuous use and 7 days of drug withdrawal.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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