培米替尼副作用有哪些?

Side effects of pemetinib

1. Digestive system discomfort, such as nausea, vomiting, diarrhea, stomach discomfort and loss of appetite. These side effects are often mild and can be alleviated by dietary modification, divided meals, and medication.

2. Skin reactions, such as rash, flushing and itching. Some patients may experience dry, flaky skin and an itchy rash. These skin reactions are usually mild or moderate and may be treated with appropriate supportive care to relieve discomfort.

3. Metabolic side effects, such as may affect protein synthesis and interfere with lipid metabolism, leading to hypoalbuminemia, hyperlipidemia or hypolipidemia, etc. In addition, allergic reactions may occur after long-term use, such as chills, fever, nausea, vomiting, diarrhea, loss of appetite, etc. Some patients may also have headaches, dizziness, depression, drowsiness, and mental confusion.

4. The impact on the blood system may lead to bone marrow suppression, manifested as a decrease in white blood cells and thrombocytopenia. Some may develop anemia, coagulation disorders, bleeding, infection, etc.

Other possible side effects include cardiovascular symptoms, hair loss, proteinuria, renal failure, etc.

The side effects of pemetinib are dealt with as follows:

1. Digestive system discomfort: such as nausea, vomiting, diarrhea and other symptoms, you can try to adjust your diet, such as eating in multiple meals and avoiding greasy and irritating foods. If symptoms are severe, consider using antiemetics or antidiarrhea medications to relieve symptoms.

2. Skin reactions: For symptoms such as rash, flushing and itching, the skin should be kept clean to avoid irritation and infection. Symptoms can be relieved with allergy medications or topical ointments.

3. Metabolic side effects: such as hypoalbuminemia, dyslipidemia, etc. Diet adjustments or drug treatment can be carried out according to the doctor's recommendations to maintain normal metabolic levels.

4. Impact on the blood system: such as bone marrow suppression, leukopenia, etc., which require regular blood routine monitoring and timely detection and treatment. White blood cell-raising drugs or other supportive treatments may be used to relieve symptoms.

5. Other side effects: such as cardiovascular system symptoms, hair loss, proteinuria, etc., should be treated accordingly according to specific symptoms. If you have severe discomfort or suspected allergic reaction, you should stop taking the medicine immediately and seek medical advice.

Pemetinib may cause serious side effects, including:

1. Eye problems.

Certain eye problems are common with pemetinib but can also be serious. Eye problems include dry eye or eye inflammation, inflammation of the cornea (the front part of the eye), increased tears, and retinal (inner part of the eye) disease. Before starting treatment with pemetinib, you will need to see an eye specialist for a complete eye exam, every 2 months for the first 6 months, and then every 3 months during treatment with pemetinib.

Tell your healthcare provider right away if you have any vision changes during treatment with pemetinib, including: blurred vision, flashes of light, or seeing dark spots. You may need to see an eye specialist immediately.

For more information on the treatment of eye side effects of pemetinib, please click: This article will provide a detailed introduction to the side effects.

2. High phosphate levels in the blood (hyperphosphatemia) and the accumulation of minerals in different tissues of the body.

Hyperphosphatemia is common with pemetinib but can be serious. High concentrations of phosphate in the blood may cause minerals such as calcium to accumulate in different tissues in the body. Your doctor will check your blood phosphorus levels during treatment with pemetinib.

Your doctor may recommend changes in your diet or phosphate-lowering therapy, or change, interrupt, or stop your pemetinib treatment as needed.

3. If the patient experiences any muscle spasms, numbness or tingling around the mouth, please tell the doctor immediately.

4. If you have vision or eye problems, kidney problems, liver problems, are pregnant or plan to become pregnant, you should inform your doctor before taking the medicine.

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