What is the domestic price of cabozantinib

Cabozantinib is a multi-target tyrosine kinase inhibitor mainly used to treat malignant tumors such as advanced renal cell carcinoma and hepatocellular carcinoma. As a targeted therapy drug, it can effectively inhibit tumor angiogenesis and tumor cell growth. The drug was developed by the American company Exelixis under the trade name Cabometyx and has been approved for use in many countries.

What is the domestic price of Cabozantinib

Understanding the price information of is very important for patients to formulate treatment plans. Drug prices are greatly affected by factors such as specifications and origin, and prices are for reference only.

Drug Price

The export price of the Turkish version of the original drug Cabometyx is: 20mg*30 pills, approximately US$2,576, 40mg*30 pills, approximately US$2,576, and 60mg*30 pills, approximately US$2,889.

The generic version of 20mg*90 tablets produced by Bangladesh Ziska is about US$165, India's NATCO's cabozantinib is about US$48 for 20mg*30 tablets, 40mg*30 tablets is about US$83, and 60mg*30 tablets is about US$136.

How to purchase

Currently, cabozantinib has not yet been officially launched in China. Patients in need can obtain it through two ways. One is to apply for special import through the hospital, and the other is to purchase the overseas version through formal cross-border medical platforms. No matter which method you choose, it is recommended to proceed under the guidance of a professional physician.

When purchasing drugs, be sure to confirm the supplier’s qualifications and ask for complete drug certification documents, including import approval documents, inspection reports, etc. Avoid purchasing through informal channels to prevent buying fake and inferior products.

Precautions when using cabozantinib

The correct use of cabozantinib is very important to reduce side effects.

Common adverse reactions

Taking cabozantinib may cause diarrhea, fatigue, loss of appetite and other reactions. About 40% of patients will develop high blood pressure and need to monitor blood pressure regularly. The incidence of hand-foot skin reaction is relatively high, manifesting as redness, swelling, and pain on the palms or soles of the feet.

Usage for special groups

Patients with liver dysfunction need to adjust the dose. For patients with moderate liver impairment, it is recommended that the starting dose be reduced to 40mg/day. Pregnant women are prohibited from taking this drug, and women of childbearing age must take reliable contraceptive measures while taking the drug. Elderly patients need to be closely monitored for adverse reactions when taking medication.

Live vaccines should be avoided during medication. If surgery is required, medication must be stopped 3 weeks in advance. Perform regular urine tests to monitor proteinuria.

How to take cabozantinib

Standardized medication methods can reduce the occurrence of adverse reactions.

Instructions for use

Cabozantinib should be swallowed whole and should not be crushed or chewed. It is recommended to take it on an empty stomach, preferably 1 hour before or 2 hours after a meal. Taking medicine at a fixed time every day will help maintain stable blood concentration. If you forget to take a dose and the next dose is less than 12 hours away, skip that dose.

Recommended dosage

The standard recommended dosage is 60 mg once daily. The dose can be gradually reduced to 40 mg or 20 mg according to adverse reactions. Patients with light body weight or small body surface area can start with 40 mg. Dosage adjustments must be made under the guidance of a physician.

Drugs must be stored in their original packaging and placed in a dry environment below 25°C. Keep medicine out of the reach of children. Any medication issues should be consulted with the attending physician in a timely manner and do not adjust the medication plan on your own.