What versions of larotrectinib are there? How much do they cost?

Larotinib is the world's first approved broad-spectrum anti-cancer targeted drug. Its different versions and price information are of great significance for patients to choose treatment options. This article will introduce in detail the existing versions of larotrectinib, the price differences of each version, and the availability in the Chinese market.

What versions of larotrectinib are there

currently on the market mainly includes the original drug and multiple generic versions. Each version has differences in quality and price.

Original drug version

The original drug jointly developed by Bayer and Loxo Oncology, the trade name is Vitrakvi. This version has been approved for marketing in many countries around the world and has the most stringent production technology and quality standards.

Laos generic version

The generic version produced by Lucius Pharmaceuticals in Laos has been approved by the Lao Food and Drug Administration. This version is relatively low-priced and widely circulated in Southeast Asia.

Bangladesh generic version

The generic version produced by Bangladesh Everest Pharmaceuticals and Yaopin International has been approved by the Bangladesh Food and Drug Administration. Both versions are well accepted by patients in developing countries.

After understanding the different versions, price is an important consideration in patient selection. The price differences of each version will be analyzed in detail below.

How much do different versions of larotrectinib cost?

The prices of various versions of larotrectinib vary significantly. The prices are for reference only. Patients can choose the appropriate treatment plan according to their own conditions.

Original drug price

Original drugs are included in domestic medical insurance and enjoy medical insurance reimbursement. You can consult the hospital or the medical insurance department for specific prices.

Prices of generic drugs in Laos

Larotinib produced by Lucius in Laos is 100mg*30 tablets, with a price of about US$206 per box. Based on standard dosage, the monthly treatment cost is approximately US$620.

Price of generic drugs in Bangladesh

The price of products of the same specification produced by Bangladesh Everest and Yaopin International is about US$549 per box. The monthly treatment cost is about US$1,647, which is 2.6 times that of the Laos version.

In addition to the international version, understanding the accessibility of the drug in the Chinese market is particularly important for domestic patients.

The launch and medical insurance status of larotrectinib in China

Larotrectinib has officially entered the Chinese market and has been included in the scope of medical insurance reimbursement.

Domestic marketing status

In April 2022, larotrectinib was approved for marketing by the China State Food and Drug Administration under the trade name Vitaika. The indications are patients with NTRK gene fusion-positive solid tumors.

Medical insurance reimbursement policy

This drug has been included in the 2023 National Medical Insurance Drug Catalog. The reimbursement ratio varies according to local policies, with an average of 50%-70%.

Domestic supply channels

It is currently supplied through designated medical institutions and specialty drug pharmacies, and must be purchased with a genetic test report and a prescription from a specialist.

Larotinib is a prescription drug, and patients should choose the appropriate version under the guidance of their doctor. When purchasing, be sure to go through formal channels to ensure the quality of the drugs. Regular genetic testing and efficacy evaluation are required during treatment.