The latest price of larotrectinib in 2024 published on the entire website

Introduction: Larotrectinib, as a broad-spectrum anti-cancer drug, has received widespread attention around the world in recent years. Its efficacy against different tumor types is remarkable, bringing new treatment hope to many patients. The following is an overview of the latest prices of larotrectinib original drugs and generic drugs in 2024, as well as a detailed analysis of drug interactions of this drug.

Larotinib price overview

1. Original drug: German Bayer larotrectinib capsules

25mg*56 tablets: 15,340$ per box; 100mg*56 tablets: 52,000$ per box. As an original drug manufacturer, Bayer’s product prices are usually higher, but the quality is guaranteed.

Germany's Bayer Oral Solution

Specifications and price: 20mg/ml, 18228$ per box, the oral solution provides patients with more variety of medication options, especially suitable for patients with dysphagia.

2. Generic drugs: Bangladesh Everest

Specifications and prices: 100mg*30 capsules, 4520$ per box. The generic drugs produced by Bangladesh Everest ensure the efficacy while being more affordable.

Bangladesh Yaopin International

Specifications and prices: 100mg*30 capsules, 4,000$ per box. Yaopin International’s generic drugs are also known for their high cost performance, providing patients with more choices.

Laos Lucius

Specifications and price: 100mg*30 capsules, 1950$ per box. Lucius Pharmaceuticals’ Lao version of larotrectinib has become the first choice of many patients with its extremely competitive price.

Drug interactions of larotinib

1. Effects of other drugs on larotinib

CYP3A4 inhibitors: strong and moderate CYP3A4 inhibitors: such as itraconazole, ketoconazole, etc., may increase the plasma concentration of larotinib and increase the risk of adverse reactions. Therefore, concurrent use should be avoided or, if avoidance is unavoidable, the dose of larotrectinib should be adjusted.

CYP3A4 inducers: strong and moderate CYP3A4 inducers: such as rifampicin, carbamazepine, etc., may reduce the plasma concentration of larotrectinib and weaken its efficacy. It is also necessary to avoid concurrent use or adjust the dosage if necessary.

2. Effects of larotinib on other drugs

Sensitive CYP3A4 substrates: Larotinib may increase the plasma concentration of certain CYP3A4 substrates (such as diazepam, lorazepam, etc.), thereby increasing the risk of adverse reactions. Therefore, patient response needs to be closely monitored during combined use and the dose adjusted if necessary.