苯巴那酯治疗癫痫需要注意什么？有副作用吗？

Cenobamate is a sodium channel blocker approved by the U.S. Food and Drug Administration (FDA) for the treatment of partial-onset epilepsy in adults. In two adequate and well-controlled clinical studies, cenobamate significantly reduced the frequency of partial-onset epilepsy, and up to 20% of patients achieved zero seizures during the maintenance period. This shows that the therapeutic effect of this drug is very good. So what should we pay attention to when treating epilepsy? Are there any side effects?

People who are allergic to any of the ingredients in cenobamate should not use this medicine.

Phenobarate treatment is also contraindicated in patients with a genetic problem that affects the heart's electrical system, called familial short QT syndrome.

Treatment with phenobarate may result in drug reactions with eosinophilia and systemic symptoms (DRESS)/multiple organ hypersensitivity reactions. Patients who develop such symptoms during drug treatment should seek medical attention immediately and seek medical help. If it is indeed caused by phenobarate, use of the drug should be stopped immediately.

Antiepileptic drugs (AEDs), including cenobamate, increase the risk of suicide, so patients should be monitored for suicidal thoughts or behavior and/or any unusual changes in mood or behavior while receiving this drug.

Phenobutate side effects

Like most drugs, treatment with phenobarate will cause some side effects. Side effects of phenobarate include: eosinophilia and systemic symptoms (DRESS)/multiple organ hypersensitivity reactions, shortened QT interval on electrocardiogram, suicidal behavior, somnolence and fatigue, dizziness, cognitive dysfunction, visual changes, risk improvement, etc. Each patient's condition and personal constitution are different, and the side effects and degree of side effects will also be different. Patients need to follow the doctor's instructions and use the medicine correctly during treatment. If serious side effects occur, they should contact the doctor in time.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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