肾移植术后病人服用雷帕鸣的护理

(sirolimus) has been further promoted and applied since it was approved by the US FDA in 1999. The drug has also been approved for marketing in China, providing great help in the treatment of many domestic kidney transplant patients. In order to achieve better treatment results, it is particularly important for patients to receive certain care. So, what does the care for patients taking rapamycin after kidney transplantation include?

1. Instruct patients to take medicine correctly

Patients are instructed to take the medicine once every 24 hours. The taking time is determined according to the specific condition of the patient. The focus is to guide the patient to strictly abide by the medication time and improve patient compliance. Rapamin (sirolimus tablets) is recommended to be used in combination with cyclosporine and corticosteroids, taken orally once a day. Bioavailability of tablets after crushing, chewing, or cutting has not been established, so it is best to swallow the tablets whole. Patients should start taking sirolimus as soon as possible after transplantation. To minimize differences in sirolimus absorption, the drug should be taken regularly with or without food.

2. Strengthen oral care

Evaluate the patient's oral hygiene status, physical condition, oral mucosal changes and drinking ability, regularly measure the patient's oral pH value, and perform pharyngeal finger culture on the patient's oral secretions. When the pH value is in the range of 5-6, it is acidic, and the probability of mold growth is high. It is advisable to use 1% hydrogen peroxide or 3% sodium bicarbonate for oral care at night; when the pH value is high and alkaline, gargle with chlorhexidine acetate gargle. The chlorhexidine acetate gargle contains chlorhexidine and metronidazole, which has a powerful bactericidal function and can effectively inhibit bacteria.

3. Psychological care

When patients develop oral ulcers, they experience pain, which affects their ability to eat. Coupled with the side effects of transplant rejection, it can easily lead to depression and anxiety, leading to a refusal to eat due to pain, which can easily lead to malnutrition. The cause of oral ulcers should be patiently explained to the patient, and the patient should be guided to strengthen oral care and informed of the importance of oral care. Stabilize the patient's mood so that he can accept and actively cooperate with treatment. If you have difficulty eating, you can follow your doctor's advice for intravenous hypernutrition treatment to ensure adequate nutrition.

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