雷帕鸣的治疗效果

It is suitable for patients undergoing kidney transplantation to prevent organ rejection. It was approved for marketing in the United States in 1999 and is currently on the market in my country. It is recommended to be used in combination with cyclosporine and corticosteroids. Rapamin treatment should be started as soon as possible after transplantation. The recommended loading dose for kidney transplant patients is 6 mg and the maintenance dose is 2 mg/day. Take orally, once daily.

In addition to China, India has also launched the generic version of rapamycin produced by Biocon, which is favored by patients because of its relatively low price. However, some patients are worried about the effects of generic drugs. Let’s take a look at it together.

A generic drug is a copy of a brand-name drug that is identical in dosage, safety, potency (regardless of how it is taken), quality, effects, and indications. Therefore, the therapeutic effects of drugs that meet the regulations are basically the same as those of the original drugs, and patients do not need to worry about the effects.

Let’s take a look at the manufacturer of the Indian version. Biocon India, one of India's top three biotech companies, is an emerging global biopharmaceutical company that is committed to reducing the cost of treatment for chronic diseases such as diabetes, cancer and autoimmune disease patients by leveraging India's cost advantages, partnering with healthcare systems around the world to provide affordable healthcare solutions.

Effect: The direct target of rapamycin may be a protein mammalian'rOR (mTOR) that has a homologous sequence to phospholipid phthaloinositide kinase. That is, the combination product of rapamycin and FKBP complex with mTOR can block the immune response triggered by activation of mTOR by H, -2, U, -15 or CD28/B7 costimulatory pathways, thus exerting a strong immunosuppressive effect. In clinical trials, patients using rapamycin effectively reduced the risk of organ rejection and prolonged the patient's survival.

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