雷帕鸣治疗什么病

What diseases does Biocon India treat?

Sirolimus was originally developed as a low-toxicity antifungal drug for the prevention of organ rejection in patients undergoing kidney transplantation. Used in combination with cyclosporine and corticosteroids. In 1977, sirolimus was discovered to have immunosuppressive effects; in September 1999, the US FDA approved sirolimus to prevent organ transplant rejection; on May 28, 2015, sirolimus tablets were approved to treat a rare lung disease, lymphangioleiomyomatosis (LAM).

Sirolimus is taken orally once daily. The loading dose of rapamin should be taken for the first time, which is 3 times the maintenance dose. The recommended loading dose for kidney transplant patients is 6 mg and the maintenance dose is 2 mg/day.

Although in clinical trials, the loading dose of 15 mg and the maintenance dose of 5 mg/day of rapamin (sirolimus tablets) were safe and effective, the therapeutic benefits of doses above 2 mg are not yet clear for kidney transplant patients. The overall safety profile of patients taking rapamycin sirolimus 2 mg daily is better than that of patients taking rapamin sirolimus tablets 5 mg daily.

The therapeutic effect of Rapamin (sirolimus tablets) is significant. Taking Rapamin for treatment will also produce certain side effects or adverse reactions, including: peripheral edema/hypertension/edema/chest pain/deep vein thrombosis/pulmonary embolism/headache/pain/dizziness/acne vulgaris/hypertriglyceridemia/diabetes/ovarian cyst/constipation/diarrhea/stomatitis, etc.

The therapeutic effect of sirolimus is remarkable, but the price of the original drug Rapamide is relatively high, which is a big burden for patients who need to take this drug for long-term treatment. Many patients choose India's Biocon Repamin. Biocon India is one of the three largest biotechnology companies in India and an emerging global biopharmaceutical company. If patients want to purchase the cost-effective Rapamin, they can consult with domestic reliable overseas medical service organizations (such as Medical Companion Travel).

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