Can crizotinib be purchased in the hospital?

As a multi-target inhibitor, crizotinib can simultaneously inhibit the activities of protein kinases such as ALK, ROS1 and c-Met. In tumors positive for ALK or ROS1 fusions, abnormal activation of these protein kinases leads to uncontrolled proliferation and survival of tumor cells. Crizotinib works by binding to the ATP binding pockets of these protein kinases and blocking their activity, thereby inhibiting the proliferation and growth of tumor cells. Crizotinib is currently on the market in China and is included in medical insurance. Patients can purchase it domestically at a price ranging from 6,000 to 12,000 yuan. Since the price of medical insurance policies varies greatly in various places, please consult your local pharmacy or medical insurance bureau for specific prices. There are original and generic versions of crizotinib available abroad. The original version is mainly Pfizer’s original drug, and the price is around 11,000 yuan. Generic drugs are mainly from Bangladesh and Laos. Due to different pharmaceutical manufacturers and drug specifications, generic drugs cost around 2,700~3,000 yuan. Moreover, the ingredients of foreign original drugs and generic drugs are basically the same as those of domestic drugs.