What are the adverse reactions of taking Regorafenib tablets?

Adverse drug reactions most commonly observed in patients treated with Regorafenib in randomized placebo-controlled trials (≥20%) were pain (including gastrointestinal and abdominal pain), HFSR, fatigue/fatigue, diarrhea, decreased appetite/food intake, hypertension, infection, dysphonia, hyperbilirubinemia, pyrexia, mucositis, weight loss, rash, and nausea. Adverse reactions found during post-approval use of regorafenib include allergic reactions, nephrotic syndrome, heart failure, arterial (including aorta) aneurysms, dissections and ruptures. If symptoms of discomfort occur, you should inform your doctor promptly.