Can Delamanid and bedaquiline be taken together?

Delamanid (Delamanid) and bedaquiline are approved for multidrug-resistant tuberculosis (MDR-TB) and have different mechanisms of action. When using medications, you should follow your doctor's instructions and tell your doctor about all the medicines you are taking, including prescription drugs, over-the-counter drugs, and other supplements. Studies have shown that the new anti-tuberculosis drugs delamanid and bedaquiline, used alone or sequentially in the treatment of patients with multidrug-resistant tuberculosis, show good efficacy and safety in combination with the background regimen recommended by WHO. Clinical trials have shown that an optimized background regimen combined with delamanid for 6-8 months resulted in a sputum culture conversion rate of 65% at 8 weeks and a good outcome rate of 75% after 24 months.