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Is selumetinib not a targeted drug?
Selumetinib is a targeted drug. It belongs to the class of MEK (Mitogen-Activated Protein Kinase Kinase) inhibitors and exerts its effect by selectively inhibiting MEK1 and MEK2, which can effectively weaken the pleiotropic effects of the Ras-Raf-MEK-ERK cascade. By inhibiting this oncogenic pathway, selumetinib reduces cell proliferation and promotes pro-apoptotic signaling. Because selumetinib is a targeted drug, it acts on tumor cells more precisely and has less toxic side effects than traditional chemotherapy drugs.
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