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Is Selinexor tablets targeted or chemotherapy?

Author: medicalhalo
Release time: 2026-02-01 22:25:32

Selinexor (Selinexor) is an orally bioavailable, selective inhibitor of nuclear export compounds that inhibits the novel therapeutic targetexportin-1 (XPO1), which is overexpressed in multiple myeloma (MM) and is responsible for the transport of nuclear proteins to the cytoplasm, including tumor suppressor proteins. Targeting XPO1 in Multiple Myeloma The rationale for XPO1 mirrors that in other tumor types, where XPO1 has been shown to be overexpressed. Inhibition of this process has shown significant antimyeloma activity in preclinical studies, either alone or in combination with established multiple myeloma therapies. Therefore, selinesol is a type of targeted drug.

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