What are the effects of Avatrombopag maleate tablets?

Avatrombopag (Avatrombopag) is a thrombopoietin receptor (TPOR; MPL) agonist with possible megakaryopoiesis-stimulating activity, where it stimulates megakaryocytic proliferation and differentiation of myeloid progenitor cells, leading to increased platelet production. After administration, avatrombopag binds to and stimulates the platelet thrombopoietin receptor (TPOR), which can cause megakaryocytes to proliferate and differentiate from myeloid progenitor cells. This process increases platelet production and may help prevent chemotherapy-induced thrombocytopenia (CIT). TPOR is classified as a member of the cytokine receptor and hematopoietic receptor superfamilies.