What are the side effects of Avatrombopag?

In clinical studies of avatrombopag, the most common adverse reactions reported by at least 3% of patients were fever, abdominal pain, nausea, headache, fatigue, and peripheral edema. Hyponatremia was also a rare serious side effect of the drug. Adverse reactions leading to discontinuation include anemia, pyrexia, and myalgia. After avatrombopag was marketed, adverse events including allergic reactions including pruritus, rash, choking sensation, erythema, pharyngeal edema, general itching, macules, facial swelling, and tongue swelling also occurred. Because avatrombopagis a thrombopoietin (TPO) receptor agonist, TPO receptor agonists have been associated with thrombosis and thromboembolic complications in patients with chronic liver disease.