How long does it take for Vonoprazan to work?

Vonoprazan(Vonoprazan)reaches its maximum effect on stomachpH within30 minutes after administration. VonorazanThrough several cytochromesP450 (CYP)isomer metabolism, mainly CYP3A4, followed by CYP3A5, CYP2B6, CYP2C19, CYP2C9 and CYP2D6. Sulfotransferases and glucuronosyltransferases are also involved in the metabolism of vonoprazan and none of the metabolites are pharmacologically active. 5,1CYP3A4converts vornoprazan into metabolites M-I and M-II , and then converted into glucuronic acid conjugation products M-I-G and M-II-G respectively. 2Unlike proton pump inhibitors, the presence of CYP2C19polymorphisms does not have a significant effect on the pharmacokinetics of vonoprazan. If you want to get more high-quality information, you can contact Yaode, and Yaode will do its best to help you learn more about high-quality overseas drugs.