What is the general market price of a box of acalatinib/acalatinib capsules?

Acalabrutinib is a selective second-generation Bruton's tyrosine kinase (BTK) inhibitor that is widely used to treat a variety of hematological malignancies. Its main purpose is to treat diseases such as chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and relapsed or refractory mantle cell lymphoma (MCL). Compared with the first-generation BTK inhibitors, acotinib has higher selectivity and lower off-target activity, so it has certain advantages in terms of tolerability and long-term safety. Multiple overseas studies have shown that acotinib can effectively delay disease progression and improve patients' progression-free survival time, providing a more promising treatment option for patients with hematological tumors.

In the Chinese market, acotinib has been officially approved for marketing and included in the medical insurance directory. The implementation of this policy has significantly reduced the financial pressure on patients and improved the accessibility of drugs. According to common specifications, the market price of each box of 100mg*8 tablets and 7 plates is about 20,000 yuan. After medical insurance reimbursement, the patient's out-of-pocket portion will decrease. The specific amount needs to be combined with local medical insurance policies and reimbursement ratios. For patients with hematological tumors who require long-term maintenance treatment, medical insurance coverage undoubtedly provides guarantee for the sustainable use of drugs.

It is worth mentioning that with the expansion of the global pharmaceutical industry chain, generic drugs of acotinib have appeared in some overseas markets. These generic drugs have the same ingredients and dosage specifications as the brand-name drugs, and are usually offered at a lower price. For example, the price of a 100mg*60-tablet generic version of acotinib produced by a Lao pharmaceutical company is about more than 2,000 yuan per box, which is far lower than the price of the domestic original drug. Moreover, the ingredients of the generic drug are consistent with the original drug. When choosing overseas channels, patients need to take the guidance of doctors to ensure that the sources of medicines purchased are formal and safe.

Reference materials:https://www.calquence.com/