How much does a box of Acotiamide cost?

Acotiamide is a drug that has attracted much attention in the field of digestion and is mainly used for the treatment of functional dyspepsia. Functional dyspepsia is a common but complex gastrointestinal disease. Patients often feel full, upper abdominal discomfort and early satiety after eating, which has long-term problems with their quality of life. The pharmacological mechanism of acotiamide is to inhibit acetylcholinesterase, thereby prolonging the action time of acetylcholine in the synaptic cleft, enhancing the movement of gastrointestinal smooth muscles and gastric emptying function, and fundamentally improving the symptoms of indigestion caused by neurotransmitter dysfunction.

The drug was first approved for marketing in Japan in 2013 and was subsequently put into use in Russia and other countries. At present, it has not been officially launched in China, and the original drug has not been included in the national medical insurance catalog. This means that Chinese patients still need to obtain drugs through overseas channels if they need them. Japan and Russia are currently the main supply markets for acotiamide, among which the Japanese version of the drug is more commonly used. The common specification is 100mg*100 tablets, and the price per box is about more than 500 yuan. The price will fluctuate due to the impact of exchange rates and import and export channels. In contrast, the pricing in the Russian market is also close to that of Japan, but due to regional differences and sales systems, prices may fluctuate slightly.

For domestic patients, the current method of purchasing drugs is relatively limited, and most of them purchase drugs through formal cross-border drug purchasing channels or third-party international pharmacies. However, special attention should be paid to the fact that there are certain risks in purchasing drugs overseas. Therefore, before using, be sure to ensure that the source is legitimate, and the drugs should be used rationally under the guidance of a doctor. Since acotiamide has not yet been approved in China, clinicians may have limited experience in using the drug. Therefore, patients need to be more cautious and avoid adjusting the dosage on their own or using it in combination with other drugs to prevent adverse reactions or drug interactions.

Reference: https://www.rad-ar.or.jp/siori/english/search/result?n=33322